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FORMADRIVE™ May Elicit Muscle Hardening effects along with a decrease in water retention and fat deposits. Formadrive ELITE™ has anti estrogen and anti aromatase activity, while at the same time driving testosterone levels significantly higher and reducing cortisol levels. Formadrive Elite™ is for the Athlete looking for good body recomposition and muscle growth. For even greater effects stack with Testavate 500™ and Thermo Bombs™.

Research suggests that Acacetin has anti-aromatase properties.* Aromatase is the enzyme responsible for converting testosterone to estrogen. Inhibition of the aromatase enzyme helps reduce the amount of testosterone that gets converted to estrogen. Healthy regulation of the aromatase enzyme can help support healthy testosterone and estrogen levels!

A new understanding of healthy estrogen metabolism is providing a natural treatments for these and other important conditions confronting both women and men.

Fortunately, phytonutrients discovered in cruciferous vegetables offer a natural approach to resolving estrogen imbalance. Dietary supplementation with an absorbable form of one of these phytonutrients, called Di-Indoly Methane (DIM), helps promote healthier estrogen metabolism. DIM's hormonal balancing effects have revealed these midlife problems are not due to estrogen itself alone, but rather, to estrogen metabolism imbalances.

Q. What is DIM, and how can it help hormones?

A. DIM is a phytonutrient (plant nutrient) found in cruciferous vegetables. These include cabbage, broccoli, bok choy, Brussels sprouts, cauliflower, kale, kohlrabi, mustard, rutabaga, and turnip. These plants have been cultivated for thousands of years and were initially used for their medicinal benefits. The connection between DIM and hormones like estrogen has to do with similar characteristics between them at the molecular level. DIM is not an estrogen or a hormone, but like estrogen it shares the common characteristic of being poorly soluble in water. Like estrogen, DIM can be metabolized only by a special class of cytochrome enzymes that reside in cell membranes in the non-water part of cells. It turns out that DIM, when consumed in food or in absorbable formulations, encourages its own metabolism. This special metabolic pathway for DIM, and the enzymes involved, precisely overlap with the pathway needed for healthy estrogen metabolism.

Stated simply, supplementing the diet with DIM specifically promotes beneficial estrogen metabolism and helps restore a healthy hormonal balance.

Accumulating experimental and clinical evidence has indicated that tumor-initiating or cancer stem-like cells are a sub-population of tumor cells capable of initiating and driving tumor growth, and cancer stem-like cells are resistant to most current cancer therapies, including chemo- and radiation therapy. More effective targeted-therapeutic approaches are urgently needed to eliminate cancer stem-like cells. Here, we report that broussoflavonol B, a chemical purified from the bark of the Paper Mulberry tree (broussonetia papyrifera), exhibited potent growth inhibitory activity towards estrogen receptor (ER)-negative breast cancer SK-BR-3 cells at sub-micromolar concentrations. Broussoflavonol B more potently inhibited growth and induced differentiation of stem-like SK-BR-3 cells-compared to the anti-estrogen tamoxifen. In addition, broussoflavonol B treatment also reduced the steady, state levels of the Human epidermal growth factor receptor-2 (HER2) and ER-36, a variant of ER-.




†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to treat, diagnose, cure or prevent any disease.

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